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Image Search Results
Journal: Arthritis Research & Therapy
Article Title: Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats
doi: 10.1186/s13075-018-1547-6
Figure Lengend Snippet: Collagen-induced arthritis (CIA) enhanced osteopontin (OPN) and cartilage oligomeric matrix protein (COMP) expression in paw joint cartilage, while the Bi-Qi capsule or methotrexate (MTX) treatment reduced this effect. Representative immunohistochemistry images of paw joint synovium with OPN and COMP immunostaining
Article Snippet: After blocking of non-specific binding sites with 10% normal goat serum for 1 h, the sections were incubated overnight at 4 °C with mouse-anti-COMP antibody (Boiss antibodies company, Beijing, China) in PBS or
Techniques: Expressing, Immunohistochemistry, Immunostaining
Journal: Arthritis Research & Therapy
Article Title: Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats
doi: 10.1186/s13075-018-1547-6
Figure Lengend Snippet: Bi-Qi capsule (BQ) or methotrexate (MTX) reduced collagen-induced arthritis (CIA)-induced osteopontin (OPN) and cartilage oligomeric matrix protein (COMP) upregulation in serum, and mRNA and protein levels in paw joint tissue. a, b OPN and COMP levels in serum. c, d OPN and COMP mRNA expression in paw joint cartilage. e, f OPN and COMP protein quantification from immunohistochemistry images of paw joint synovium. Data are presented as mean ± SD from eight rats in each group. Significant effect of treatment compared to control: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 . Significant effect of treatment compared to arthritic group: #### P < 0.0001 . Significant effect of treatment compared to high-dose BQ (BQ-HD): $$ P < 0.01, $$$$ P < 0.0001 . Significant effect of treatment compared to MTX-group: & P < 0.05, &&&& P < 0.0001. BQ-MD, moderate-dose BQ
Article Snippet: After blocking of non-specific binding sites with 10% normal goat serum for 1 h, the sections were incubated overnight at 4 °C with mouse-anti-COMP antibody (Boiss antibodies company, Beijing, China) in PBS or
Techniques: Expressing, Immunohistochemistry, Control